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As well as the environments through which these components are processed should really normally be taken care of in a very clean up state and shielded from external resources of microbial contamination. Inner contamination in the clear rooms should also be prevented just as much as you possibly can by making certain aseptic technique at Each indivi
) the place the active component comprises a major percentage of the tablet and where by control of fat may be presumed to generally be an satisfactory control of drug information uniformity. Weight variation just isn't an sufficient indication of material uniformity wherever the drug substance comprises a comparatively minor part of the tablet, or
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